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Some health related topics are guaranteed to stir up heated
2019-06-19
Some health-related topics are guaranteed to stir up heated debate in the general public whenever they nrf2 keap1 crop up in the news. Publishing a research paper on chronic fatigue syndrome, homoeopathy, or mode of childbirth is a recipe for a media field day, a lively letters section, and a jamme
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Para Estados Unidos Argentina no ha sido comercialmente rele
2019-06-19
Para Estados Unidos, Argentina no ha sido comercialmente relevante SR 49059 pesar de que ocupó el puesto 29 entre sus destinos de exportación, y que las ventas norteamericanas aumentaron más del doble en relación a lo que importó del país latinoamericano. Incluso, casi 85% del total de las exportaci
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br Sebastian Vollmer and colleagues April conclude
2019-06-19
Sebastian Vollmer and colleagues (April, 2014) conclude that “the contribution of economic growth to the AG957 in early childhood undernutrition in developing countries is very small, if it exists at all”. Progress will therefore require a shift from “the so-called trickle-down approach of a grow
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The functional analysis of this
2019-06-19
The functional analysis of this V1764fsX1786 mutation is shown in Fig. 3B; no current was observed, indicating severe loss-of-function. Although we did not investigate the mechanisms of this complete reduction in Na+ current in this mutation, Herfst et al [19]. reported a similar frameshift mutation
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Since the Food Safety Standards Authority of India
2019-06-18
Since 2006, the Food Safety Standards Authority of India has led efforts to promote food safety, tighten food laws, and harmonise these laws with international standards and quality-management systems. These efforts need to be complemented with interventions focused on practices at the household lev
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Curiosamente las dos obras que pueden
2019-06-18
Curiosamente, las dos obras que pueden considerarse germinales del pensamiento complejo, tales como Ciencia con consciencia e Introducción al pensamiento complejo, son obras de recopilación de trabajos dispersos, aunque ramificados lógicamente. Antes que tratados sistemáticos y elaborados desde el p
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br Materials and methods br Results and discussion ABT is
2019-06-18
Materials and methods Results and discussion ABT-737 is a BH3-mimetic targeting Bcl-2, Bcl-XL and Bcl-W. The aim of the experiments was to test whether inhibition of Bcl-2 and Bcl-XL using ABT-737 can eradicate the CD34+/CD38− AML cell population. Bone marrow MNCs from patients (Table 1) were
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Despite taking hydroxyurea for months
2019-06-18
Despite taking hydroxyurea for 6 months, his leukocytosis, splenomegaly, and constitutional symptoms were poorly controlled and his performance status and overall function had declined even further. There was little clinical benefit to gain by increasing the hydroxyurea dose further especially in th
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When the subject of climate change
2019-06-18
When the subject of climate change is raised, people tend to think of extreme heat events, droughts, violent storms, rising sea levels, and floods. Today, we certainly live in an era of severe weather events, which will intensify if human-driven climate change continues unabated. Such events are kno
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The lack of a single identified
2019-06-18
The lack of a single identified correlate of protection for LAIV should not deter future immunogenicity studies in resource-limited settings, especially using systems vaccinology approaches designed to dissect the complex interplay of innate and adaptive pathways following vaccination. John C Victor
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In response to the lack of
2019-06-18
In response to the lack of epidemiological information on typhoid in Africa, the Typhoid Fever Surveillance in Africa Programme (TSAP), funded by the Bill & Melinda Gates Foundation and covering ten countries and 13 sites across Africa, was established between 2010 and 2014. In this kinesin spindle
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Seratrodast Several true lumen re entry devices
2019-06-18
Several true lumen re-entry devices have been introduced into the market, including the Outback catheter, allowing fluoroscopically controlled true arterial lumen re-entry after subintimal guidewire passage. A recent retrospective review reported a successful re-entry rate of 91% in 11 patients with
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This Ca overload activates the forward mode of the Na
2019-06-18
This Ca2+ overload activates the forward mode of the Na+/Ca+ exchanger (NCX), increases the transient inward current (Iti), and induces ventricular arrhythmias due to delayed after depolarizations (DADs). Subtypes of CPVT Several subtypes of CPVT have been reported (Table 1). The most common typ
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In DC from A group only
2019-06-18
In DC from A group only few genes appeared to be significantly and highly modulated (10 out of 84). The HIV natural ligands CCL4 and CD4, the HIV induced transcription factor IRF1 as well as the apoptotic genes BAD and CASP8 resulted down-regulated compared to monocytes at all the considered time po
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In our study the levels of BALP
2019-06-17
In our study, the levels of BALP, PINP and β-CTx in the serum were significantly (pbone Dihydro-β-erythroidine hydrobromide markers indicate that the bone formation and bone absorption occur at the same time in patients with BM. Another feature of our research was that we used BTMs clinically to pr
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