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p2x7 receptor In patients who develop bone metastases
2019-04-19
In patients who develop bone metastases, these are commonly diagnosed at the time of their initial work up for their metastatic disease (∼80%) [7], although others can develop skeletal metastases at any time during the disease course. The consequences of bone metastases include pain (∼80%) [3,6,8] a
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LQTS is classified into subtypes LQT to LQT
2019-04-19
LQTS is classified into subtypes LQT1 to LQT13 based on the site of genetic mutation. Each type possesses distinct clinical characteristics and a different prognosis. Treatment choice depends partly on individual phenotype and partly on genotype. Among Asian countries, several reports have been publ
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La sensaci n de desmoronamiento y de v
2019-04-19
La sensación de desmoronamiento y de vértigo nace en “Lumbre en el aire” de la confusión de lo terrestre con lo estelar o sideral. Mientras los signos “jardines”, “mar” o “rocas” remiten a realidades telúricas, “cielo”, “astros”, “cometas”, “aerolitos” “galaxia” sitúan al lector en la dimensión cósm
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Article of the Universal Declaration of Human Rights
2019-04-19
Article 25 of the Universal Declaration of Human Rights states that “everyone has the right to a standard of living adequate for the health and well-being of himself and of his family, including food, clothing, housing and medical care and necessary social services, and the right to security in the
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In the past three decades
2019-04-19
In the past three decades, along with rapid economic growth in China, there has been a striking increase in alcohol consumption, greater than in most other parts of the world (). Although the histamine receptors drinking level in China used to be far lower than in many high-income and middle-income
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Este nuevo orden de lo latinoamericano ha
2019-04-19
Este nuevo orden de “lo latinoamericano” ha afectado también en el estatuto de otras disciplinas, entre ellas literatura comparada, estudios étnicos, latinidad norteamericana, Caribe, sociología, pensamiento teológico y hasta en una nueva dimensión hemisférica de los American Studies. Son muchas las
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Demand for kidney transplantation for ESKD has already outst
2019-04-18
Demand for kidney transplantation for ESKD has already outstripped the supply of donated adiponectin receptor from living donors, notwithstanding the inadequate donor pool. End-of-life donation can potentially expand the donor pool but is less common. For example, in India, among the 12 294 renal t
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MiR a rs is situated in the passenger
2019-04-18
MiR-196a2 rs11614913 is situated in the 3′ passenger strand mature sequence of miR-196a2. The C to T mutation of the rs11614913 SNP, which was located in the stem region of an miR-196a-2 precursor, leads to a change from a G:C to a G:U mismatch. A previous study has shown that miR-196a2 rs11614913 c
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br Analysis of mismatch repair function and results
2019-04-18
Analysis of mismatch repair function and results Analysis of microsatellite instability: Multiplex PCR amplification of 5 mononucleotide microsatellite loci was performed using the MSI Analysis System (Promega). Amplification products were analyzed using the ABI 3500Dx capillary electrophoresis i
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PF2341066 Supplier br Conflict of interest br Introduction O
2019-04-18
Conflict of interest Introduction Over the last several decades, substantial research interest has been focused on characterizing the pathophysiological substrate underlying atrial fibrillation (AF) [1]. AF is a complex arrhythmia and has been shown to be temporally variable, so that AF durati
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Upon examining his previous hospital records from years prio
2019-04-18
Upon examining his previous hospital records from 4 years prior, we found that he was diagnosed with acute heart failure at the second hospitalization 1 week after catheter ablation for atrial fibrillation. His symptoms and chest radiographic findings had improved by standard therapy for heart failu
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br Conclusion Accumulating clinical data suggest
2019-04-18
Conclusion Accumulating clinical data suggest the presence of a genetic component in the pathogenesis of AF. In addition to the gene mutations identified in familial AF, the candidate gene approach and GWAS identified genetic risks in the non-familial form of AF. In multiple Western populations,
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br Radiotherapy for bone metastases As a palliative interven
2019-04-17
Radiotherapy for bone metastases As a palliative intervention, radiotherapy is effective and efficient at treating painful bone metastases, and the side effects associated with its use are manageable and usually self-limiting in nature. Between 50% and 80% of patients gain at least partial relief
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br Discussion PLSVC can be encountered for
2019-04-17
Discussion PLSVC can be encountered for the first time during electrophysiological procedures. It is the most common variation in the thoracic venous system and is estimated to be present in 0.3–0.5% of the general population and in 5–10% of patients with other congenital heart defects [3]. It ca
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Despite our best efforts the cause
2019-04-17
Despite our best efforts, the cause of SCD in young individuals is sometimes not established; no cause is identified in up to 40% of cases. Importantly, whether a cause of death is established or not, the possibility of an underlying inherited cardiac disorder remains in many cases, including the po
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