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Sca mice demonstrate deficiency in MMP
2018-11-06
Sca-1−/− mice demonstrate deficiency in MMP activity and enhanced fibrosis in muscle (Kafadar et al., 2009). In addition, these mice develop insulin resistance and glucose intolerance when exposed to a HFD (Staszkiewicz et al., 2012). Recent studies suggest that Sca-1+ lactone in the adipose SVF are
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br Materials and methods br Verification and
2018-11-06
Materials and methods Verification and authentication Karyotyping and PCR analysis were performed at the Reproductive & Genetic Hospital of CITIC — Xiangya. Twenty metaphase BKM120 were observed and all had a normal karyotype of 46, XX. The results of PCR-RFLP assay confirmed a pathogenic CAG
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The widespread hope for a
2018-11-05
The widespread hope for a new era of prevention and treatment for chronic neurological disorders, such as stroke, Alzheimer\'s disease, and Parkinson\'s disease, will likely depend on the discovery of new CNS drugs. However, currently over 99% of candidate CNS drugs fail in clinical tests because of
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br Experimental Procedures br Author Contributions br
2018-11-05
Experimental Procedures Author Contributions Acknowledgments We thank Drs. Lenhard Rudolph and Jianwei Wang (Germany Research Group on Stem Cell Aging, Germany) for the shRNA library and helpful suggestions about this work, and Dr. Markus Grompe (Oregon Health & Sciences University) for Fan
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br The configuration of the
2018-11-05
The configuration of the system for photochemical reaction imaging The system is placed in a compact case that is effectively an intraoral camera with a built-in emitter. The camera field of view at a working distance from the object (about 15 mm) is 1 cm2. The construction of the system provides
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br Vacancy impurity interactions in the aluminum lattice
2018-11-05
Vacancy – impurity interactions in the aluminum lattice The supercell contained 2×2×2 cubic unit cells of the FCC aluminum lattice. The calculations were performed using an energy cutoff of 600eV for the plane-wave basis set and 2×2×2 k-points grid in the Brillouin zone. Such a choice of the main
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The results of Poisson regression are shown
2018-11-05
The results of Poisson regression are shown in Table 2 (men) and 3 (women). Age-adjusted PRs (95% CIs) for each outcome by survey year and p-values for temporal trends are presented. Although point estimates varied by year, the associations of SRH and health behavior with SES were observed, with som
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purchase HG-9-91-01 Although the findings in this paper cont
2018-11-05
Although the findings in this paper contribute new insights to our understanding of the complex relationship between informal care provision and health, nevertheless the study poses certain limitations which necessitate caution in the interpretation of the findings. Firstly, the nature of the data w
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It is well established that work can influence health
2018-11-05
It is well-established that work can influence health and wellbeing in both positive and negative ways (Ross & Mirowsky, 1995; LaMontagne & Keegel, 2009; van der Noordt, IJzelenberg, Droomers, & Proper, 2014). There also evidence that persons with disability have poorer health and wellbeing compared
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br Statistical analyses We estimate
2018-11-05
Statistical analyses We estimate one model for each health outcome. For the physical markers of health, as well as self-rated health we estimate model 1, while for the health behaviour outcomes we estimate model 2:where Y is the outcome variable; MAB is the maternal age at the time of birth for t
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br Distinguishing features of and selected
2018-11-05
Distinguishing features of, and selected tensions within, a model-based perspective A model-based perspective emphasizes the processes producing outcome variation, and observed data are used to characterize that data-generating process. This is the majority perspective in statistical textbooks, i
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The study adds to the literature
2018-11-05
The study adds to the literature on place of death by focusing on a sub-Saharan African country, Zambia, where adult mortality is high and has been largely attributed to HIV/AIDS. Zambia\'s National Health Policy recognizes the large unmet need of and necessity to upscale palliative care services fo
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International comparisons are also valuable for studies eval
2018-11-05
International comparisons are also valuable for studies evaluating the population-level number of deaths attributable to a behavioral risk factor because these studies often rely on estimates of death risks from the behavioral factor under investigation (Preston & Stokes, 2011; Rostron, 2011). In su
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Research quantifying community capacity has identified stati
2018-11-05
Research quantifying dgat inhibitor capacity has identified statistically significant differences amongst neighbourhoods (Jung & Rhee, 2013) and between towns (Lovell et al., 2015a), thus confirming the importance of place to our social relationships. Place is recognised by geographers as those aspe
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br Conflicts of Interest br Author Contributions br
2018-11-05
Conflicts of Interest Author Contributions Acknowledgments This work was supported by a Grant-in-Aid for Scientific Research (KAKENHI) from the Japan Society for the Promotion of Science (JSPS) and the Japanese Ministry of Education, Culture, Sports, Science and Technology (MEXT) (Grant num
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