• Since antithrombotic therapy for patients with AF is

  2019-05-17

  

  Since antithrombotic therapy for patients with AF is rapidly changing with the increasing use of dabigatran, rivaroxaban, and apixaban, some of the primary issues that will influence the future revision of various guidelines (HRS [Heart Rhythm Society], ESC [European Society of Cardiology], ACC [Ame

• Climate change will have far reaching effects on how

  2019-05-17

  

  Climate change will have far-reaching effects on how we build, organise, and manage health systems as complex institutions. Yet, to date, these challenges have largely been ignored by the research community. Despite substantial work by WHO on the interface between climate and health, two major confe

• It means an opportunity As we concern

  2019-05-17

  

  It means an opportunity. As we concern ourselves with the prominence of health in the new agenda, it\'s easy to forget that (human) development is by definition people-centred, and that living a long, healthy, and creative life is its cornerstone. The expansion of the new goals to encompass many (if

• La cr tica realizada al ccpor las diferentes comisiones deve

  2019-05-16

  

  La crítica realizada al ccpor las diferentes comisiones develó la verticalidad en la toma de decisiones políticas, las cuales se agudizaban cuando se realizaban acciones militares, lo que ocasionó constantes fricciones y sanciones LY 379268 disodium salt algunos miembros de la Comisión Militar o de

• ICE was introduced as a real time imaging technique to

  2019-05-16

  

  ICE was introduced as a real-time imaging technique to assist catheter ablation procedures. Chu et al. performed an ICE-guided catheter ablation in 9 dogs. They concluded that ICE can accurately guide catheter ablation directed at anatomic landmarks. They also used ICE to confirm the endocardial con

• ERS and BrS are thought to represent manifestations of

  2019-05-16

  

  ERS and BrS are thought to represent 2 manifestations of the JWSs. Both syndromes are associated with vulnerability to development of polymorphic VT and VF leading to SCD [1–3,15] in young adults with no apparent structural annexin v disease and occasionally to sudden infant death syndrome [25–27].

• La estructura del libro apuesta por plantear problemas pero

  2019-05-16

  

  La estructura del libro apuesta por plantear problemas, pero no por una solución única. De ahí que el desenlace de los capítulos previos sean dos re-flexiones distintas, pero complementarias: por un lado, la precaria fijación textual de un texto “condenado CM-272 existir en una forma que me gustaría

• br We appreciate the response by Sharath

  2019-05-16

  

  We appreciate the response by Sharath Nagaraja and Ritesh Menezes to our Comment, in which we had argued that patients with tuberculosis deserve a complete and patient-centric solution, irrespective of whether they seek care in the public or private health sector. Nagaraja and Menezes seem to have

• br En el contexto argentino

  2019-05-16

  

  En el contexto argentino comprendido entre las décadas del treinta y del cincuenta, la legitimación del elemento indígena —en su diálogo con los sustratos hispano-colonial e inmigratorio— es emprendida por muy pocos intelectuales provenientes del campo del ensayismo de interpretación nacional. Baj

• br A KCNJ mutation corresponding to an S L mutation

  2019-05-16

  

  A KCNJ8 mutation, corresponding to an S422L mutation in the protein, was first identified in a 14-year-old girl with early repolarization [59], who suffered frequent VF attacks. KCNJ8 encodes Kir6.1, which has 2 transmembrane regions, and the KATP channel is composed of a complex of Kir6.1 or Kir6

• br Discussion ELT is a well

  2019-05-16

  

  Discussion ELT is a well-recognized complication of a dual chamber pacing system.[1,2] This is a wide QRS tachycardia resulting from the sensing of retrograde P-waves by the pacemaker, consequently triggering ventricular pacing beyond the programmed PVARP. Retrograde P-waves are induced by ectopi

• Introduction Personalized medicine is the major goal of tran

  2019-05-16

  

  Introduction Personalized medicine is the major goal of translational research in the post-genomic era. Numerous biomarkers have been identified by genomic or proteomic approach that can reclassify the disease Schaftoside and predict clinical outcome. However, to define a specific disease phenotyp

• Since BM impairs the balance between bone formation and bone

  2019-05-16

  

  Since BM impairs the balance between bone formation and bone resorption, altered bone remodeling activities can be assessed directly by measuring the components of affected bone cells or indirectly by analyzing metabolic products released from the bone matrix by changed rates of bone formation or re

• Any abnormality causing a loss

  2019-05-16

  

  Any abnormality causing a loss-of-function in the IKs macromolecular complex may lead to adrenergic-induced imbalance in ventricular repolarization currents and consequent QTc prolongation, which is identified based on the defective response of IKs to PKA stimuli due to mutations in KCNQ1 (-G269S, -

• Preamble The J wave syndromes JWSs consisting of the Brugada

  2019-05-16

  

  Preamble The J-wave syndromes (JWSs), consisting of the Brugada syndrome (BrS) and early repolarization syndrome (ERS), have captured the interest of the cardiology E-64 over the past 2 decades following the identification of BrS as a new clinical entity by Pedro and Josep Brugada in 1992 [1]. The

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