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One of our most intriguing
2018-10-30
One of our most intriguing findings in the present study is that decreased goblet cell differentiation and mucus production were associated with severe inflammation in response to DSS in Adam17Mx1-Cre+ mice. Complete knockout of the Adam17 gene displays multiple pathological changes in several organ
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The recent Zika virus ZIKV outbreak has been
2018-10-30
The recent Zika virus (ZIKV) outbreak has been declared a Public Health Emergency of International Concern (PHEIC) by the World Health Organization in February 2016. It started in Brazil in 2015, rapidly spread through South and Central America, and is expected to reach the continental US in the sum
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br Materials and Methods br Results br Discussion Previous
2018-10-30
Materials and Methods Results Discussion Previous studies have indicated that irisin could improve dyslipidemia and hepatic steatosis in mice (Xiong et al., 2015). The decrement of lipid accumulation in hepatocytes was proposed to result mainly from the suppression of triglyceride synthesis
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Notably the arrival reticulocyte count contributed strongly
2018-10-30
Notably, the arrival reticulocyte count contributed strongly to the predictive score, being significantly higher on day 1 than at steady state for 2°ACSs (272±88 vs 237±95, respectively p=0.006, n=33 paired values), while the VOC group\'s values were stable (p=0.98). Moreover, increased reticulocyte
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Zinc is an essential nutrient for microbial growth
2018-10-29
Zinc is an essential nutrient for microbial growth, but can be toxic in excess (Blencowe and Morby, 2003; Coleman, 1998). The delicate balance between zinc sufficiency and toxicity is maintained by bacterial metal homeostasis systems (Klaus, 2005; Moore and Helmann, 2005). The GAS metalloregulator,
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The shape of the observed PK concentration
2018-10-29
The shape of the observed PK concentration-time profile following IH administration was consistent with the IM PK profile (Fig. 3). Plasma oxytocin was detectable in all subjects at the first sampling time (3min post-dose) and remained quantifiable in 5/16 subjects up to 4h following IM administrati
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Ahora bien tal y como se muestra
2018-10-29
Ahora bien, tal y como se muestra en la Imagen 1, el sistema tributario mexicano que funcionó desde 1917 hasta 1935 se conformaba de once grandes rubros fiscales cobrados y administrados por la shcp. En términos generales, cuando un contribuyente no atendía al pago de las contribuciones se le determ
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br Data The physical data for input parameters of
2018-10-29
Data The physical data for input parameters of different materials used for designing a highly efficient CIGS solar cell have been presented in Table 1. Along with this dataset, the contact parameters and the conditions under which the simulation was conducted have been demonstrated in Tables 2 a
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br Acknowledgements Many thanks to C Johnson for
2018-10-29
Acknowledgements Many thanks to C. Johnson for providing unpublished data. This research was supported by an Australian Postgraduate Award and Australian Government Caring for our Country 2 Target Area Grant 2013/14 (Project ID: TAG14-00542) Bettongia tropica population status, viability and impa
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Technological innovation is an essential driver of
2018-10-29
Technological innovation is an essential driver of human and economic development. It can improve the functioning of markets (), promote government accountability (), build human capital (), and reduce the risks we face from global environmental change (). Yet designing technologies that improve the
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Several previous studies have shown that by the
2018-10-29
Several previous studies have shown that by the age of 7-months, the voice region of the temporal cortex manifests selective activation to human speech and non-speech vocal sounds (Blasi et al., 2011; Grossmann et al., 2010; Lloyd-Fox et al., 2011). Our results provide converging evidence, by showin
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Adolescents in this study averaged over h of sleep per
2018-10-29
Adolescents in this study averaged over 8h of sleep per night, which is similar to what has been obtained in other studies with this age group (Wolfson and Carskadon, 1998; Fuligni and Hardway, 2006) and is close to the number of hours recommended for adolescents (Wolfson and Carskadon, 1998). Yet,
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br Acknowledgments This work was
2018-10-29
Acknowledgments This work was supported by a grant from the Ministry of Health, Labour and Welfare (Research for Intractable Diseases), and a Ministry of Education, Culture, Sports, Science and Technology. SM and KK contributed equally to this work. We would like to gratefully and sincerely thank
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De manera m s radical creemos que no solo estamos
2018-10-29
De manera más radical, creemos que no solo estamos ante nuevos discursos sobre la sexualidad y otras prácticas, sino ante un nuevo tipo de sujeto. No es posible explorar esta hipótesis en este artículo, pero es importante plantearla, porque no podremos entender SAR 405 cabalidad los procesos sociale
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Estas continuidades entre mercados sexuales
2018-10-29
Estas continuidades entre mercados sexuales comerciales que traspasan las diferencias culturales y legales han llevado entacapone Laura Agustín a cuestionar la relevancia misma de la ley en el campo del sexo comercial (Agustín 2008). Dada la dominancia de las soluciones legales tanto en las respuest
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