Introduction Wiskott Aldrich syndrome WAS

2018-10-20

Introduction Wiskott-Aldrich syndrome (WAS) is a severe X-linked primary immunodeficiency resulting from mutations in the WAS gene; WAS encodes a hematopoietic-specific and developmentally regulated cytoplasmic protein (WASp). WASp is a key regulator of the FLAG tag Peptide cytoskeleton, specifica

Purmorphamine cost Adult stem cells are defined as undiffere

2018-10-20

Adult stem cells are defined as undifferentiated, multipotent progenitor cells with the capability to both self-renew and generate differentiated progeny throughout the lifetime of an organism (Alonso and Fuchs, 2003; Blanpain and Fuchs, 2006; Fuchs and Segre, 2000; Lavker and Sun, 1983; Lavker et a

Nintedanib We generated mouse strains suitable for

2018-10-20

We generated mouse strains suitable for humanization by introducing loss-of-function KIT receptors (W41 or Wv alleles) into NOD/SCID Il2rg (NSG; NSGW41, NSGWv) or BALB/c Rag2Il2rg (BRgWv) mice (Cosgun et al., 2014). These mice efficiently support stable engraftment of human hematopoietic stem and pr

Hello world!

2018-07-29